![]() ![]() One review showed that acetaminophen had little benefit in the management of osteoarthritis. Which one is more effective?Īcetaminophen controls pain and fever but does not control inflammation so for conditions such as muscle sprains and cramps, ibuprofen will be more effective. Do not take more ibuprofen than recommended without consulting your doctor. If you are taking ibuprofen over-the-counter, the maximum recommended daily dose is 1200mg. Ibuprofen tablets/capsules can be given every four to six hours. Like acetaminophen, it is better suited for the treatment of acute pain. Pain-relieving effects last for approximately four hours. Ibuprofen is a short-acting NSAID, with a relatively quick onset of action. In some cases (see below) a lower maximum dose (3000mg/day) should not be exceeded. Pain-relieving effects last for three to four hours however, it is important acetaminophen is not taken more often than every four to six hours, and the maximum of 4000mg (4 grams) per day (24 hours) is not exceeded. See also: Compare Tool - Acetaminophen vs Ibuprofen Which one works for longer?Īcetaminophen and ibuprofen both work for a similar length of timeĪcetaminophen is short acting with a relatively quick onset of action. include Advil, Genpril, Midol IB, Motrin IB, and Proprinal. Brands of ibuprofen available in the U.S. This makes it effective at relieving pain and reducing inflammation, but there is a risk of stomach-related side effects. It is considered a nonselective NSAID because it blocks both COX-2 enzymes (involved in pain signaling and inflammation) and COX-1 enzymes (associated with a protective effect on stomach lining). ![]() Ibuprofen blocks COX enzymes, but to a different extent than acetaminophen. Ibuprofen is a type of NSAID that relieves pain. Acetaminophen may be called paracetamol in some countries. Even though acetaminophen works on COX enzymes, it is not considered a NSAID. Experts aren't sure exactly how acetaminophen works but believe it affects COX enzymes in the brain, reducing the formation of prostaglandins (prostaglandins are substances released during injury that cause pain and inflammation). Unlike NSAIDs, such as ibuprofen, it does not reduce inflammation. Either acetaminophen or ibuprofen may be used for headaches, fever and minor aches and pains, but ibuprofen is more effective for strains or sprains.Īcetaminophen brand names include Tylenol, Aceta, Apra and Mapap.Any medication used for pain relief should be taken at the lowest effective dose for the shortest possible time. Acetaminophen appears to have more adverse effects than traditionally thought, and this risk increases with higher dosages.This risk is low if no more than 1200mg of ibuprofen is taken per day. Ibuprofen is a NSAID so is not suitable for everybody and can cause gastrointestinal (GI) adverse effects, cardiovascular adverse effects, and kidney toxicity.Some research suggests NSAIDs such as ibuprofen are more effective than acetaminophen at relieving pain.Acetaminophen is only effective at relieving pain and fever, while ibuprofen relieves inflammation in addition to pain and fever. ![]()
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